Live stem cells are not used in AnteAGE. Rather, we grow human bone marrow stem cells under special conditions in labs and then extract only cytokines and growth factors, discarding everything else. AnteAGE products contain these cytokines and growth factors, which are proteins encapsulated in natural lipid envelopes to preserve them, keep them functional, and aid in transporting these rejuvenating agents.

No, neither.

Our stem cells are sourced only from the bone marrow of young, healthy, pre-screened adult donors. Stem cell cytokines also contain none of the original cell parts themselves, only the beneficial growth factors they produce.

We source our stem cells from the bone marrow of young, healthy, pre-screened adult donors. The cells are cultured in a laboratory, within a controlled environment that fosters production of the biosignals that will engage in skin repair and rejuvenation. We then harvest and extract the powerful growth factors and cytokines inside, discarding the cell itself. Our products are 100% free of inflammatory cells, cell fragments, RNA, or DNA.

Mesenchymal stem cells originating from bone marrow are the most powerful and versatile population in your body, able to transform into myriad cell types to fight injury and inflammation. As they leave the bone marrow and travel throughout the body, these stem cells act as command and control centers, directing the process of healing to minimize overall damage. We can't live without these cells, and yet we have fewer of them working for us with each passing day.

Cellese Regenerative Therapeutics cultures these cells in-vitro, providing them with a controlled environment to foster production of biosignals engaged in skin repair and rejuvenation. We harvest these Growth Factors & Cytokines they produce and use them as our products' primary active.

Mesenchymal stem cells (MSC) are special types of stem cells that are pluripotent and can differentiate into a variety of cell types including bone, cartilage, and muscles. They direct reparative biochemical functions by secreting a pattern of biosignals called cytokines, which begin a chain of communication with other cells to perform tasks that are orchestrated by the MSCs. The concentration and specific cytokine patterns they generate depends on the physiologic role from where they are sourced. This means that adipose-derived stem cells are programmed to produce new fat cells, and bone marrow stem cells are programmed to migrate to injuries and to regenerate new bone, tissue, or cartilage. However, in labs they can be manipulated and triggered to perform specific tasks regardless of their origin, such as generating elastin or fibroblasts despite originating from bone marrow.

All bone marrow stem cells used to cultivate our biosignals and growth factors are from adult female donors. They ethically sourced from state of the art, certified laboratories.

Plant stem cells are undifferentiated cells that can communicate with other plant cells to grow or regenerate all parts of a botanical.

Plant stem cells do not produce signals that can communicate with human cells, and human cells do not have receptors for plant biochemicals. Because they cannot communicate with each other, plant stem cells are unable to influence human cellular activity or stimulate a direct cellular response to grow new tissue, such as collagen. Plant stem cells act as antioxidants in skincare products, and—like many antioxidants commercially available—can offer an anti-inflammatory effect, protect against UV-induced oxidative stress, and can nourish skin cells. The American Academy of Dermatology has outlined the role plant stem cells play in skincare. https://www.aad.org/media/news-releases/new-technology-could-make-antioxidants-in-skin-care-products-more-effective

Conditioned media is the blend of nutrients that remain after filtering cells for unwanted materials.

Stem cells are not all alike. The scientists that developed AnteAGE believe that bone marrow stem cells are the most effective source because they are what command and control tissue repair and healing throughout the body. Unlike bone marrow stem cells, adipose (lipid or fat) derived stem cells are not programmed towards wound repair, and are primarily used to generate more fat cells. They also contain more pro-inflammatory pattern of cytokines and growth factors, and inflammation is not something AnteAGE believes should be promoted in skin on a daily basis. Bone marrow stem cells do the opposite by countering and calming inflammation. Fibroblasts are connective tissue in the body that produces collagen, but are not stem cells. In cosmetics, they have typically been sourced from human foreskins. Although they aren’t stem cells, fibroblasts produce some biosignals, but not as many as bone marrow stem cells, which can be 15 to 50 times more bountiful.

Very few ingredients are able to reach the dermis where stem cells reside to activate them. However, irritation will trigger an immune response in the body that will activate stem cells to identify damage and migrate to injured areas to begin reparative cellular activity. This means that any pro-inflammatory ingredient that irritates skin or induces an allergic reaction could be considered a stem cell activator because stem cells in skin are a defense mechanism that detects damage and responds by migrating to injured cells and creating healing cytokines, growth factors, and mRNAs.